Effectiveness and the patient experience with vortioxetine vs other standard-of-care antidepressants in major depressive disorder: Real-world insights from an observational, prospective, decentralized study using the PatientsLikeMe platform

Journal of Affective Disorders Reports 2026 Open access

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Authors: Jeoffrey Bispham, Chris Blair, Sagar V. Parikh, Roger S. McIntyre, Mark G. A. Opler, Erlyn Macarayan, Mary C. Burke, Alina Karim, Michael L. Martin, Priscilla Driscoll Shempp, Ian Robinson, Maggie McCue
DOI: 10.1016/j.jadr.2025.101019
Cited by: 0
References: 40

Abstract

• Qualitative usability tests show need for accessible support interfaces like PLM • Vortioxetine or other SOC AD led to similar proportions with PGI-I

Fields of Study & Subjects

Treatment of Major Depression Digital Mental Health Interventions Tryptophan and brain disorders

Publication details

Journal / source
Journal of Affective Disorders Reports
Volume
24
Pages
101019–101019
Publication date
9 January 2026
Language
EN