Exploring the relationship between Ayurgenomics and bio-psycho-social symptoms in cancer care

BACKGROUND: Ayurveda, the ancient Indian system of medicine, emphasises the role of individual constitution in health. Modern Ayurgenomics integrates Ayurvedic principles with genomic analysis, aiming to personalize Yogic interventions for cancer patients. OBJECTIVE: The current study aims to explore the intersection of Ayurgenomics, dehaprakriti, and Yoga Therapy in the context of medical oncology. METHOD: The study included 60 chemotherapy patients, with their dehaprakriti assessed using AyuSoft. Patients' symptoms were diagnosed with the Rotterdam Symptom Checklist (RSCL). The data was analyzed to observe any correlation between Prakriti type and chemotherapy response. RESULTS: Vatapradhan types show high physical impairment (38.96) but retain functionality (13.83). Pittapradhan types have minimal physical burden (24.05) but high psychological strain (13.00) with a positive life outlook. Kapha-dominant types experience moderate physical (27.78-34.61) and psychological burdens (9.69-12.12) and slower disease progression. Major findings revealed that vata-dominant patients required more immediate intervention due to rapid tumor growth, while pitta-dominant patients were more susceptible to chemotherapy side effects. Patients with kaphaprakriti showed slower tumor growth. Appropriate Yogic interventions and dietary adjustments may help manage the loss of vitality during chemotherapy. CONCLUSION: The study highlights the growing relevance of integrating traditional Eastern wisdom, such as Ayurveda, with Western scientific approaches to personalize cancer care. Integrating Prakriti-based Yogic interventions may alleviate the physical and psychological impact of cancer and its treatments, enhancing the overall quality of life for patients.