Anesthetic considerations for therapeutic whole-lung lavage in acquired pulmonary alveolar silico-proteinosis: A case report

JCA advances. 2026 Open access

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Authors: Sri Rama Ananta Nagabhushanam Padala, Kumbhar Prathamesh Gurudas, Nishant Varlani, Abhinav Choubey, Yogesh Kumar Niwariya, Ashutosh Kaushal, Dhiraj Chopra
DOI: 10.1016/j.jcadva.2026.100233
Cited by: 1
References: 11

Abstract

Pulmonary alveolar proteinosis is a rare disorder characterized by intra-alveolar surfactant accumulation resulting in severe impairment of gas exchange. Whole-lung lavage (WLL) remains the definitive therapy but presents significant anesthetic challenges, including lung isolation, risk of hypoxemia, large-volume fluid instillation, and hemodynamic instability. We describe the anesthetic management of a 28-year-old male with pulmonary alveolar silico-proteinosis scheduled for therapeutic WLL. Meticulous planning and multidisciplinary coordination enabled safe completion of the procedure with successful postoperative recovery and extubation.

Fields of Study & Subjects

Neonatal Respiratory Health Research Medical Imaging and Pathology Studies Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Publication details

Journal / source
JCA advances.
Publisher
Elsevier BV
Volume
3
Issue
2
Pages
100233–100233
Publication date
19 April 2026
Language
EN