Anti-CLEC7A nanobody in situ engineering promotes amyloid-β oligomers clearance by CAR-microglia to alleviate Alzheimer's disease pathology in mice

Journal of Controlled Release 2026

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Authors: Chongzheng Yan, Zhichao Kong, Yuxue Pan, Zhipeng Fu, Kun Han, Xiaotian Zhao, Jing Zhang, Longyu Bo, Weiyi Sun, Jinxin Gao, Xianghui Dong, Zuolin Zheng
+4 more Xiao Yue, Peng Sun, Xinyi Jiang, Chen Chen
DOI: 10.1016/j.jconrel.2026.114710
Cited by: 3
References: 22

Fields of Study & Subjects

Alzheimer's disease research and treatments Neuroinflammation and Neurodegeneration Mechanisms Glycosylation and Glycoproteins Research

Publication details

Journal / source
Journal of Controlled Release
Publisher
Elsevier BV
Volume
392
Pages
114710–114710
Publication date
15 February 2026
Language
EN