Bleomycin-induced flagellate dermatitis after sclerotherapy for venous malformation: A case report

JAAD Case Reports 2026 Open access

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Authors: Dajana Smoljan, Vedrana Bulat, Mislav Mokos, Reinhart Speeckaert, Slavko Gašparov
DOI: 10.1016/j.jdcr.2026.01.061
Cited by: 1
References: 9

Abstract

Bleomycin is a glycopeptide antibiotic composed mainly of bleomycin A2 and B2, produced by Streptomyces verticillus. It is used widely in oncology, including in testicular cancer, Hodgkin and non-Hodgkin lymphomas, and squamous cell carcinoma, and is also administered intralesionally for vascular malformations. Its therapeutic action relies on DNA binding and the induction of strand breaks that halt cellular proliferation.

Fields of Study & Subjects

Chemotherapy-related skin toxicity Vascular Malformations and Hemangiomas Sympathectomy and Hyperhidrosis Treatments

Publication details

Journal / source
JAAD Case Reports
Publisher
Elsevier BV
Volume
70
Pages
206–209
Publication date
18 February 2026
Language
EN