Sodium thiosulfate as a potential treatment for osteoma cutis in Albright hereditary osteodystrophy: A case report

JAAD Case Reports 2026 Open access

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Authors: Margaret G. Mercante, Peyton Yee, Shira Lanyi, Barrett J. Zlotoff
DOI: 10.1016/j.jdcr.2026.02.018
Cited by: 0
References: 9

Abstract

Albright hereditary osteodystrophy (AHO) is a subtype of pseudohypoparathyroidism type 1a (PHP-1a) resulting from GNAS1 mutations.1 It is characterized by several physical features, including short stature, brachydactyly, obesity, and a round face. The phenotype also includes osteoma cutis and macular atrophic lesions representing precursors for progressive osteoma.2-4 Currently, surgical excision is the primary treatment option for osteoma cutis.5 We report a case of a pediatric patient with AHO presenting with atrophic macules representing precursors to osteoma cutis.

Fields of Study & Subjects

Dermatological and Skeletal Disorders Vascular Malformations and Hemangiomas Bone Tumor Diagnosis and Treatments

Publication details

Journal / source
JAAD Case Reports
Volume
70
Pages
175–177
Publication date
16 February 2026
Language
EN