Acute T-cell leukemia/lymphoma presenting with leukemia cutis mimicking prurigo nodularis
Abstract
Adult T-cell lymphoma/leukemia (ATLL) is a CD4+ T-cell neoplasm most commonly caused by human T-cell lymphotropic virus type 1 (HTLV-1).1 It can manifest into 4 clinical subtypes: acute, smoldering, chronic, and lymphoma.1 Initial presentation differs depending on the subtype of ATLL, often presenting with B-symptoms, hepatosplenomegaly, hypercalcemia, and elevated lactate dehydrogenase (LDH).1 ATLL is frequently associated with leukemia cutis, a condition characterized by the infiltration of neoplastic leukocytes into the skin.
Fields of Study & Subjects
T-cell and Retrovirus Studies
Cutaneous lymphoproliferative disorders research
Viral-associated cancers and disorders
Publication details
- Journal / source
- JAAD Case Reports
- Volume
- 71
- Pages
- 230–233
- Publication date
- 13 March 2026
- Language
- EN