Basosquamous carcinoma in a patient with Freeman-Sheldon syndrome
Abstract
Freeman-Sheldon syndrome (FSS) is a musculoskeletal condition that tends to involve the face, hands, feet, and is often traced to the myosin heavy chain 3 (MYH3) gene. Patients tend to have microstomia giving the appearance that they are whistling.1 Complications include feeding difficulties and dysphagia.2 From a surgical standpoint, management can be challenging because patients with FSS have been reported to develop malignant hyperthermia following exposure to general anesthesia.3
Fields of Study & Subjects
Neurogenetic and Muscular Disorders Research
Immunodeficiency and Autoimmune Disorders
Dupuytren's Contracture and Treatments
Publication details
- Journal / source
- JAAD Case Reports
- Publisher
- Elsevier BV
- Volume
- 72
- Pages
- 181–183
- Publication date
- 1 May 2026
- Language
- EN