From molecular interactions to clinical potential: Strontium–calcium polyelectrolyte synergy for biomimetic dentin repair and remineralization

The study aimed to evaluate effects of calcium carbonate (CaCO 3 ) and strontium carbonate ( SrF₂ CaCO 3 ) polyelectrolyte-cation complexes on dentin adhesive bonding, mechanical properties and intrafibrillar mineralisation of dentinal collagen fibers. Following ethical approval, dentin discs were prepared from collected human premolars and treated with 1%SrF₂ CaCO 3 , 0.5%SrF₂ CaCO 3 , 2% SrF₂ CaCO 3 and distilled water for 15 days under controlled pH. Raman spectroscopy, transmission and scanning electron microscopy were performed to evaluate intrafibrillar mineralisation and topographical changes. Diffusional coefficient and density functional theory were calculated. Resin-dentin bond specimens were prepared and microtensile bond strength was measured. Statistical analysis was performed using a one-way ANOVA with subsequent post-hoc comparisons, with significance of p