Exploratory evaluation of local hyperthermia (44 ± 2 °C) in granuloma annulare: A pilot randomized controlled study
Abstract
Granuloma annulare (GA) is a benign, noninfectious granulomatous dermatosis, typically presenting as annular erythematous papules or plaques on the dorsal aspects of the extremities or the trunk.1 Current therapeutic options are often suboptimal and associated with significant adverse effects, necessitating the development of novel strategies to enhance efficacy and minimize treatment-related morbidity. Local hyperthermia is a physical therapeutic modality that induces immunomodulatory effects by elevating tissue temperature.
Fields of Study & Subjects
Skin Diseases and Diabetes
Dermatologic Treatments and Research
Autoimmune and Inflammatory Disorders
Publication details
- Journal / source
- JAAD International
- Volume
- 26
- Pages
- 11–14
- Publication date
- 3 March 2026
- Language
- EN