Temporal trends and racial/ethnic disparities in hepatocellular carcinoma incidence in the US between 2000-2022

JHEP Reports 2026 Open access

Read full text
Authors: Wenzhan Jing, Thi T. Hang Pham, Samuel K. So
DOI: 10.1016/j.jhepr.2026.101754
Cited by: 0
References: 24

Abstract

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) in the US is largely driven by chronic hepatitis B in non-Hispanic Asians/Pacific Islanders (NH API) and chronic hepatitis C and metabolic dysfunction-associated steatotic liver disease in other racial/ethnic groups. We examined temporal trends and racial/ethnic disparities in HCC incidence in the US. METHODS: The SEER-21 database (1 January 2000-31 December 2022) was used to identify adults aged ≥30 years diagnosed with HCC. Annual percentage changes (APC) in HCC incidence were estimated using Joinpoint regression. RESULTS: = -4.8; p

Fields of Study & Subjects

Hepatocellular Carcinoma Treatment and Prognosis Global Cancer Incidence and Screening Hepatitis B Virus Studies

Publication details

Journal / source
JHEP Reports
Volume
8
Issue
4
Pages
101754–101754
Publication date
30 January 2026
Language
EN