Outcomes and management strategies of pregnancies after heart and lung transplantation across Europe

JHLT Open 2026 Open access

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Authors: Jildau R. Meinderts, Linda Wilhelmina Van Laake, Dieuwertje Ruigrok, Olivier Christiaan Manintveld, Jérôme Le Pavec, Michael Perch, Jens Gottlieb Gottlieb, Adelheid Görler, Robin Vos, Jesper M. Magnusson, Claire Merveilleux du Vignaux, Anikó Bohács
+10 more Balázs Sax, Tanel Laisaar, Vincent Bunel, Margriet E. Gosselink, Merel E. Hellemons, Kevin Damman, Jelmer Riemer Prins, A. Titia Lely, Erik A.M. Verschuuren, Margriet F. C. de Jong
DOI: 10.1016/j.jhlto.2026.100481
Cited by: 0
References: 35

Abstract

Background Literature on pregnancy after heart and/or lung transplantation (HTx, LTx, HLTx) remains sparse. This study assessed short- and long-term outcomes of pregnancies post-thoracic organ transplantation across Europe and analyzed center management of these patients. Methods European centers provided retrospective data on post-HTx/LTx pregnancies and center strategies for handling transplant recipients with a pregnancy wish. Descriptive statistics and linear regression analysis were used. Results Forty-two females had 50 pregnancies across 12 European centers. Pregnancy induced hypertension occurred in 50% (HTx), 28% (LTx) and 20% (HLTx) and preeclampsia in 19%, 16% and 20%, respectively. Preterm birth (

Fields of Study & Subjects

Cardiovascular Issues in Pregnancy Transplantation: Methods and Outcomes Pregnancy and Medication Impact

Publication details

Journal / source
JHLT Open
Volume
11
Pages
100481–100481
Publication date
7 January 2026
Language
EN