Pneumococcal serotype epidemiology and resistance after PCV13 replacement with PCV10, Sweden

Journal of Infection 2026 Open access

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Authors: Linda Yamba Yamba, Fabian Uddén, Silvana Dalence, Anouschka de Bruijn, Wiebke Köster, Jonas Ahl, Kristian Riesbeck
DOI: 10.1016/j.jinf.2026.106723
Cited by: 2
References: 29

Abstract

OBJECTIVES: To evaluate the impact of the 2018 switch from PCV13 to PCV10 in Sweden's childhood immunisation programme on the serotype distribution of Streptococcus pneumoniae. METHODS: Respiratory tract (RT) S. pneumoniae isolates (n=1615; 2020-2023) were serotyped, tested for antimicrobial susceptibility and compared with invasive pneumococcal disease (IPD) isolates (n=397) and PCV13-era data (2016-2018). RESULTS: Predominant serotypes were 3 (13%), 19A (11%), 23B (10%), and 11A (7.5%). PCV10 coverage was low (4.1%), but increased with PCV13 (29%), PCV15 (30%), PCV20 (47%) and PCV21 (71%). After reintroduction of PCV10, the proportions of serotypes 3 (8.7% to 13%) and 19A (4.5% to 11%) increased (p

Fields of Study & Subjects

Pneumonia and Respiratory Infections Respiratory viral infections research Pneumocystis jirovecii pneumonia detection and treatment

Publication details

Journal / source
Journal of Infection
Publisher
Elsevier BV
Volume
92
Issue
5
Pages
106723–106723
Publication date
12 March 2026
Language
EN