Computational analysis of mechanical performance for 3D-printed biodegradable PLA cardiovascular stents

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Authors: Yi Huang, Yan Xu, Jialu Li, Zhipeng Deng, Xinmiao Feng, Rixiang Quan, Weiting Xu, Xiaolong Chen, James P. K. Armstrong, Massimo Caputo, Cian Vyas, Paulo Bartolo
+2 more Fengyuan Liu, Giovanni Biglino
Cited by: 2
References: 36

Abstract

Cardiovascular stents are widely applied in the treatment of arterial stenosis, but conventional metallic stents present limitations such as permanent implantation, hypersensitivity reactions, and late restenosis. Biodegradable polymer stents offer a promising alternative, though their translation is restricted by structural design challenges and inadequate mechanical performance. In this study, eight representative stent architectures were computationally evaluated with respect to radial elastic recoil, foreshortening, dogboning, and radial support force. Stents were fabricated from polylactide (PLA) via fused deposition modelling (FDM), and the effects of nozzle temperature, layer height, and printing speed were systematically assessed on PLA dogbone specimens to determine optimised process parameters. Computational analysis revealed that only type B and type F stents met clinical deformation requirements, with radial elastic recoil

Fields of Study & Subjects

Coronary Interventions and Diagnostics Electrospun Nanofibers in Biomedical Applications Additive Manufacturing and 3D Printing Technologies

Publication details

Journal / source
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
Publisher
Elsevier BV
Volume
176
Pages
107355–107355
Publication date
29 January 2026
Language
EN