Multicenter Prospective Study on Transvaginal Radiofrequency Ablation of Uterine Fibroids: Efficacy, Safety, and Reproducibility

Journal of Minimally Invasive Gynecology 2026 Open access

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Authors: Ángel Santalla-Hernández, Iván Gomez- Gutierrez-Solana, María DelaTorre-Bulnes, María Eugenia Marín-Martínez, Domingo Molina-González, María Esperanza Gadea-Niñoles, Antonia María Lopez-Lopez, Irene Pelayo-Delgado, Cristina Torrijo-Rodrigo, Rosario Lara-Peñaranda, María José Palomo-Viciana, Mariña Naveiro-Fuentes
DOI: 10.1016/j.jmig.2026.01.031
Cited by: 1
References: 19

Abstract

OBJECTIVE: To evaluate the reproducibility, mid-term efficacy, and safety of transvaginal ultrasound-guided radiofrequency (RF) ablation of uterine myomas among multiple centers and operators. DESIGN: Prospective multicenter observational study. SETTING: Eleven public and private hospitals in Spain. PATIENTS: A total of 393 women with symptomatic uterine myomas treated between May 2021 and June 2024. INTERVENTIONS: All procedures were performed using a standardized transvaginal RF ablation protocol (VIVA RF System, STARmed Co., Goyang, South Korea) after formal training of participating gynecologists. MEASUREMENTS AND MAIN RESULTS: Clinical and ultrasonographic data were prospectively collected at baseline, 12, and 24 months. The mean baseline myoma volume was 35.2 ± 45.0 cm³, decreasing to 12.2 ± 24.2 cm³ at 12 months (65.3% reduction, p

Fields of Study & Subjects

Uterine Myomas and Treatments Thyroid and Parathyroid Surgery Gynecological conditions and treatments

Publication details

Journal / source
Journal of Minimally Invasive Gynecology
Publisher
Elsevier BV
Volume
33
Issue
5
Pages
615–621
Publication date
16 January 2026
Language
EN