Characteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
Abstract
Background: T-cell counts and lung infections in immunosuppressed ICU patients, offering clinical evidence to guide the management of lung infections in this population. Methods: T-cell count ≤200/µL) groups. Microecological analysis was performed on each group. Intergroup comparisons were conducted for 28-day mortality, hospital length of stay, and ICU length of stay. Results: in severe group. By day 28, four patients (50.0%) in the mild group had died compared with six (37.5%) in the moderate group and nine (56.3%) in the severe group. There were no significant difference in the duration of ICU or hospital stays. Conclusions: T-cell depletion. These findings are valuable for optimizing clinical diagnosis and treatment strategies and may contribute to improving patient outcomes.
Fields of Study & Subjects
Pneumocystis jirovecii pneumonia detection and treatment
Immune Response and Inflammation
Immunodeficiency and Autoimmune Disorders
Publication details
- Journal / source
- Journal of Intensive Medicine
- Publisher
- Elsevier BV
- Volume
- 6
- Issue
- 2
- Pages
- 157–165
- Publication date
- 8 January 2026
- Language
- EN