Successful Bacteriophage Treatment of a Recalcitrant Intra-Abdominal Infection Caused by Multidrug-Resistant Pseudomonas aeruginosa in a 2-Year-Old Child

The Journal of Pediatrics 2026 Open access

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Authors: Sanchi Malhotra, Keiko Christine Salazar, Neema Pithia, Ishminder Kaur, Kristina Adachi, Nanda Ramachandar, Austin L. Terwilliger, Anthony Maresso, Robert S. Venick, Suzanne V. McDiarmid, John S. Bradley
DOI: 10.1016/j.jpeds.2026.115005
Cited by: 1
References: 19

Abstract

Antimicrobial resistance is life-threatening to pediatric patients with medical complexity who receive multiple courses of broad-spectrum antibiotics. Bacteriophages offer a safe treatment alternative when our antibiotic armamentarium is no longer sufficient. We describe successful use of bacteriophage therapy on a patient with a recalcitrant Pseudomonasaeruginosa infection after receiving a multiorgan transplant.

Fields of Study & Subjects

Bacteriophages and microbial interactions Antibiotic Resistance in Bacteria Antibiotic Use and Resistance

Publication details

Journal / source
The Journal of Pediatrics
Publisher
Elsevier BV
Volume
291
Pages
115005–115005
Publication date
19 January 2026
Language
EN