Purmorphamine mitigates 3-nitropropionic acid-induced neurodegeneration via enhancing the brain-derived neurotrophic factor/protein kinase B/glycogen synthase kinase-3β signaling and attenuation of oxidative/nitrosative stress, neuroinflammation, and apoptosis

Journal of Pharmacology and Experimental Therapeutics 2026

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Authors: Mohamed Z. Habib, Sherif A. Kamar, Mohamed Osama Mostafa, Yasmin M. Aboul-Ela, Mohammed R. Rabei, Moataz Maher Kamel, Sara Elsayed Abdelrahman, Ahmed M. Salama, Mohamed Mahmoud Abdelrahim Elshaer, Nouran K. Olama, Nourhan Moussa, Rania M. Hadhoud
+1 more Esraa M. Elnahas
DOI: 10.1016/j.jpet.2026.104958
Cited by: 1
References: 53

Fields of Study & Subjects

Nerve injury and regeneration Neuroinflammation and Neurodegeneration Mechanisms NF-κB Signaling Pathways

Publication details

Journal / source
Journal of Pharmacology and Experimental Therapeutics
Publisher
Elsevier BV
Volume
393
Issue
7
Pages
104958–104958
Publication date
4 June 2026
Language
EN