Unraveling the mechanism of Lianqiaobaidu powder in viral myocarditis: Complementary actions within cardiac cell types

Journal of Pharmaceutical Analysis 2026 Open access

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Authors: Na Tang, Shuqiao Xing, Ting Zhou, Wen-Hui Qi, Bingyan Wang, Chengwen Li, Wei Cao, Zhi-Jing Zhao, Yingfeng Lei, Xiao-Qiang Li
DOI: 10.1016/j.jpha.2026.101595
Cited by: 1
References: 4

Abstract

• Lianqiaobaidu powder alleviates cardiac dysfunction and injury in CVB3-infected mice. • Nodakenin, Isosakuranin, and Epicatechin gallate are key LQBDP anti-VMC constituents. • Nodakenin inhibits CVB3 replication in cardiac fibroblasts via the MEK pathway. • Isosakuranin reduces inflammation in CVB3-infected macrophages via the RAGE pathway. • Epicatechin gallate blocks CVB3-induced cardiomyocyte apoptosis via the TNFR pathway.

Fields of Study & Subjects

Viral Infections and Immunology Research Traditional Chinese Medicine Analysis Andrographolide Research and Applications

Publication details

Journal / source
Journal of Pharmaceutical Analysis
Publisher
Elsevier BV
Volume
16
Issue
8
Pages
101595–101595
Publication date
2 March 2026
Language
EN