Current mass spectrometry methods for the analysis of 7-ketocholesterol and related sterols

The Journal of Steroid Biochemistry and Molecular Biology 2026 Open access

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Authors: William J. Griffiths, Mohsen Ali Asgari, Yuqin Wang
DOI: 10.1016/j.jsbmb.2026.106956
Cited by: 2
References: 25

Abstract

In this article we summarise the current mass spectrometry methods used for analysis of 7-ketocholesterol and related sterols, focusing on the advantages of the different methods with emphasis on pre-analytical and analytical precautions to avoid artefactual ex vivo formation of these oxysterols.

Fields of Study & Subjects

Cholesterol and Lipid Metabolism Mass Spectrometry Techniques and Applications Hormonal and reproductive studies

Publication details

Journal / source
The Journal of Steroid Biochemistry and Molecular Biology
Publisher
Elsevier BV
Volume
259
Pages
106956–106956
Publication date
10 February 2026
Language
EN