Flow Gradients in Severe Aortic Stenosis and Preserved Ejection Fraction: A 10-Year Transcatheter Aortic Valve Replacement Study

Journal of the Society for Cardiovascular Angiography & Interventions 2026 Open access

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Authors: Prabhjot Hundal, Zaid Abood, Niloufar Javadi, Viviana Zlochiver, Mohamed Osman, David Boulware, Jeff Hall, Renuka Jain, Suhail Q. Allaqaband, TANVIR K. BAJWA, Abdul Jamil Tajik, Muhammad Fuad Jan
DOI: 10.1016/j.jscai.2025.104117
Cited by: 0
References: 20

Abstract

Background There are limited and conflicting data on the long-term outcomes in normal-flow low-gradient (NFLG) and paradoxical low-flow low-gradient (pLFLG) aortic stenosis (AS) following transcatheter aortic valve replacement (TAVR). Methods Patients who underwent TAVR for severe symptomatic native AS with preserved left ventricular ejection fraction (≥50%) from 2012 to 2022 at our center were included. The cohort was divided into 3 different hemodynamic AS groups: high-gradient aortic stenosis (HGAS) (aortic valve mean gradient [AVMG] ≥40 mm Hg, aortic valve [AV] peak velocity ≥4 m/s, and AV area ≤1 cm 2 ), NFLG (stroke volume index ≥35 mL/m 2 , AVMG

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Aortic Disease and Treatment Approaches Infective Endocarditis Diagnosis and Management

Publication details

Journal / source
Journal of the Society for Cardiovascular Angiography & Interventions
Volume
5
Issue
2
Pages
104117–104117
Publication date
15 January 2026
Language
EN