Novel Use of Valve-in-Valve Transcatheter Mitral Valve Replacement for Severe Bioprosthetic Mitral Valve Stenosis During Pregnancy: A Case Report

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Authors: Alexander Paul Hoffmann, Yonatan Buber, James M. McCabe
Cited by: 0
References: 9

Abstract

A 26-year-old woman at 14 weeks gestation with her third pregnancy presented with severe bioprosthetic mitral valve stenosis, which represents very high maternal and fetal risk. Pregnancy termination was recommended but declined, and valve surgery was deemed to be of prohibitive risk. After multidisciplinary discussion, she underwent valve-in-valve transcatheter mitral valve replacement in the second trimester. She had an uncomplicated vaginal delivery at term. This represents a novel use of transcatheter valve replacement to stabilize a pregnant patient with a high-risk valvular lesion. This approach may be considered after multidisciplinary discussion in appropriately selected patients.

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Cardiovascular Issues in Pregnancy Congenital Heart Disease Studies

Publication details

Journal / source
Journal of the Society for Cardiovascular Angiography & Interventions
Volume
5
Issue
5
Pages
104273–104273
Publication date
10 March 2026
Language
EN