Bidirectional reallocations of sitting time, physical activity, and sleep in relation to risk of all-cause mortality and cardiovascular disease: An analysis of the Prospective Urban Rural Epidemiology (PURE)-China cohort study

Journal of sport and health science/Journal of Sport and Health Science 2026 Open access

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Authors: Yilin Huang, Jun Hao, B Hu, Y Wang, Lap Ah Tse, W Liu, Qiujing Cai, Biyan Wang, Z Liu, Tong Bu, Sumathy Rangarajan, Scott Alexander Lear
+1 more W Li
DOI: 10.1016/j.jshs.2026.101140
Cited by: 1
References: 50

Abstract

• A J-shaped association between daily sitting time and risks of all-cause mortality and cardiovascular disease was found in the PURE-China cohort, with increased risks at both low and high sitting levels. • Reallocating 30 min of sitting to physical activity in individuals sitting ≥4 h/day linked to 3%–4% lower composite outcome risk and 6%–7% lower all-cause mortality. • A “sitting paradox” was observed in those with low sedentary time (

Fields of Study & Subjects

Physical Activity and Health Obesity Physical Activity Diet Sleep and related disorders

Publication details

Journal / source
Journal of sport and health science/Journal of Sport and Health Science
Publisher
Elsevier BV
Volume
15
Pages
101140–101140
Publication date
14 April 2026
Language
EN