Precision Melphalan Dosing Using a Population Pharmacokinetic Model Combined with IL-6 Blockade (Siltuximab) in Older Adults with Multiple Myeloma Undergoing Autologous Hematopoietic Cell Transplantation: Phase II Lead-in Outcomes

Transplantation and Cellular Therapy 2026

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Authors: Natalia Tijaro Ovalle, Andrew P. Lin, Danielle Lutrario, Khayla Leiva, Joel Lamboy, Anjali B. Patel, Alyssa Kamrowski, Ryan C. Schofield, Hamza Hashmi, Hani Hassoun, Malin L. Hultcrantz, Neha Korde
+13 more Alexander M. Lesokhin, Kylee H. Maclachlan, Sham Mailankody, Sridevi Rajeeve, Urvi Shah, Carlyn Rose Tan, Saad Z. Usmani, David J. Chung, Charlotte Hughes, Michael Scordo, Heather Jolie Landau, Sergio A. Giralt, Gunjan L. Shah
DOI: 10.1016/j.jtct.2025.12.058
Cited by: 0

Fields of Study & Subjects

Multiple Myeloma Research and Treatments Hematopoietic Stem Cell Transplantation Pharmaceutical studies and practices

Publication details

Journal / source
Transplantation and Cellular Therapy
Volume
32
Issue
2
Pages
S35–S36
Publication date
1 February 2026
Language
EN