Peripheral HLA-DR+ Neutrophils, CD163+ Monocytes and Inflammatory Serum Cytokines Coincide with Severe Immune Effector Cell-Associated Neurotoxicity at Peak Toxicity Onset in CD19 CAR T cell Therapy

Tony Chour; Nikhita H. Poole; Hugh MacMillan; Katelyn Burleigh; David Richard Glass; Bobbie‐Jo Webb‐Robertson; Emily C. Liang; Jennifer Jing Huang; Alexandre V. Vinaud Hirayama; Kelly Stratton; Stanley R. Riddell; Jordan Gauthier; Heather Herd Gustafson; Evan William Newell; Sylvain Simon

doi:10.1016/j.jtct.2025.12.253

Peripheral HLA-DR+ Neutrophils, CD163+ Monocytes and Inflammatory Serum Cytokines Coincide with Severe Immune Effector Cell-Associated Neurotoxicity at Peak Toxicity Onset in CD19 CAR T cell Therapy

Transplantation and Cellular Therapy 2026

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Authors: Tony Chour, Nikhita H. Poole, Hugh MacMillan, Katelyn Burleigh, David Richard Glass, Bobbie‐Jo Webb‐Robertson, Emily C. Liang, Jennifer Jing Huang, Alexandre V. Vinaud Hirayama, Kelly Stratton, Stanley R. Riddell, Jordan Gauthier

+3 more

Heather Herd Gustafson, Evan William Newell, Sylvain Simon

DOI: 10.1016/j.jtct.2025.12.253

Cited by: 0

Fields of Study & Subjects

CAR-T cell therapy research Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses

Publication details

Journal / source: Transplantation and Cellular Therapy
Volume: 32
Issue: 2
Pages: S184–S184
Publication date: 1 February 2026
Language: EN