Phase II One Arm Multicenter Study of Early Reinfusion of Tisagenlecleucel to Promote Durable B-cell Aplasia in Pediatric and Young Adult Patients with relapsed/refractory CD19-Positive B-cell Acute Lymphoblastic Leukemia (REFUEL)

Sanam Shahid; Audrey Mauguen; Devin P. McAvoy; Kinga Hosszu; Christine L. Phillips; Liora Michal Schultz; Emily M. Hsieh; Challice Lee Bonifant; Vanessa A. Fabrizio; Brianna Bisogno; Maria Paes Pena; Nancy Chapman; Jaap Jan Boelens; Kevin Joseph Curran

doi:10.1016/j.jtct.2025.12.887

Phase II One Arm Multicenter Study of Early Reinfusion of Tisagenlecleucel to Promote Durable B-cell Aplasia in Pediatric and Young Adult Patients with relapsed/refractory CD19-Positive B-cell Acute Lymphoblastic Leukemia (REFUEL)

Transplantation and Cellular Therapy 2026

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Authors: Sanam Shahid, Audrey Mauguen, Devin P. McAvoy, Kinga Hosszu, Christine L. Phillips, Liora Michal Schultz, Emily M. Hsieh, Challice Lee Bonifant, Vanessa A. Fabrizio, Brianna Bisogno, Maria Paes Pena, Nancy Chapman

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Jaap Jan Boelens, Kevin Joseph Curran

DOI: 10.1016/j.jtct.2025.12.887

Cited by: 0

Fields of Study & Subjects

CAR-T cell therapy research Acute Lymphoblastic Leukemia research Immunotherapy and Immune Responses

Publication details

Journal / source: Transplantation and Cellular Therapy
Volume: 32
Issue: 2
Pages: S593–S594
Publication date: 1 February 2026
Language: EN