Compound EGFR Mutations Are Predominantly P-Loop and Alpha-C Helix Compressing Mutations With Increased Responsiveness to Second- Versus Third-Generation Tyrosine Kinase Inhibitors

Journal of Thoracic Oncology 2026

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Authors: Ximeng Liu, Moses H. Stamboulian, Maxime Borgeaud, Erjia Zhu, Caroline Weipert, Nicole Zhang, Monique B. Nilsson, Kaiwen Wang, Lingzhi Hong, Jinghao Wang, Benjamin B. Morris, Simon Heeke
+12 more Jacqulyne P. Robichaux, Courtney Lewis, Leylah Drusbosky, Hong Chen, Yan Yang, Junqin He, Li Cai, Jia Wu, Jianjun Zhang, Addeo Alfredo, John V. Heymach, Xiuning Le
DOI: 10.1016/j.jtho.2026.103948
Cited by: 1
References: 48

Fields of Study & Subjects

Lung Cancer Treatments and Mutations Melanoma and MAPK Pathways Lung Cancer Research Studies

Publication details

Journal / source
Journal of Thoracic Oncology
Publisher
Elsevier BV
Volume
21
Issue
10
Pages
103948–103948
Publication date
1 May 2026
Language
EN