Psychometric Properties of the EQ-5D-5L in Post-COVID-19 Condition: Results From the Long CORFU Study

OBJECTIVES: The EQ-5D-5L is commonly used to assess health-related quality of life in patients with post-COVID-19 condition (PCC), but evidence on its psychometric properties and responsiveness to change in this population is limited. This study assessed psychometric properties of the EQ-5D-5L in long-term health-related quality of life assessments of patients with PCC. METHODS: Participants from multiple Dutch COVID-19 cohorts completed a self-administered questionnaire 2 and 3 years after acute COVID-19. Measures included 13 PCC-related symptoms, the EQ-5D-5L, self-rated health (SRH), and (at 3-year follow-up) a Global Rating of Change (GRC) scale. Psychometric properties were assessed via hypothesis testing of the following: distributional characteristics (ceiling/floor), divergent validity, convergent validity, explanatory power, known-group validity, and responsiveness. RESULTS: ) (39.0% of total 41.3%). Median EQ-5D-5L index increased with higher symptom severity (P