Aortic comparison of monozygotic twins and their nontwin siblings

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Authors: Amanda M. Rushing, Anirudh Chandrashekar, Grace H. Miner, Peter L. Faries, Michael L. Marin, Daniel K. Han
Cited by: 0
References: 8

Abstract

Twin registries provide data on concordance of aneurysmal disease between twin sets, but provide no granular data. Four sets of monozygotic (MZ) twin families with aortic pathology and aortic imaging were identified within a single health care system to create a Dice score for aortic comparison. MZ twin Dice scores in families A through D were 32.3%, 34%, 46.5%, and 42.4% respectively. Nontwin siblings Dice scores were 31% and 33.2% for families B and C, respectively. Our case series illustrates that MZ twin aortas have higher rates of concordance compared with their nontwin siblings.

Fields of Study & Subjects

Connective tissue disorders research Aortic aneurysm repair treatments Aortic Disease and Treatment Approaches

Publication details

Journal / source
Journal of Vascular Surgery Cases and Innovative Techniques
Volume
12
Issue
3
Pages
102201–102201
Publication date
26 February 2026
Language
EN