The association between 10-year cardiovascular risk and fracture incidence in postmenopausal women: a prospective analysis from the Women's Health Initiative

The Lancet Regional Health - Americas 2026 Open access

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Authors: Rafeka Hossain, Deepika Laddu, Carolyn J. Crandall, Kristine E. Ensrud, Jane A. Cauley, Kelley Pettee Gabriel, Bernhard Haring, Shakia T. Hardy, Meryl S. LeBoff, JoAnn E. Manson, Ann V. Schwartz, Aladdin H. Shadyab
+2 more Nelson B. Watts, Nicole C. Wright
DOI: 10.1016/j.lana.2026.101440
Cited by: 2
References: 26

Abstract

Background: Cardiovascular disease (CVD) and fractures share pathophysiological mechanisms, yet the relationship between predicted CVD risk and fracture incidence remains unexplored. Using the PREventing cardiovascular disease eVENTs (PREVENT) score, this study aimed to determine the association between CVD risk and incident fractures in postmenopausal women. Methods: This study included 21,300 participants from the Women's Health Initiative (WHI) (1993-2024). PREVENT 10-year CVD risk was categorized as low (

Fields of Study & Subjects

Bone health and osteoporosis research Menopause: Health Impacts and Treatments Cardiovascular Health and Disease Prevention

Publication details

Journal / source
The Lancet Regional Health - Americas
Publisher
Elsevier BV
Volume
57
Pages
101440–101440
Publication date
28 March 2026
Language
EN