Bioactive metal-organic framework with efficient ROS supply ability for enhanced ferroptosis-like cancer cell death

Materials & Design 2026 Open access

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Authors: Mengping Huo, Bangzhen Ma, Lin Shi, Shouda Gao, Qi Shen, Wenting Zhang, Yafei Lin, Zaibin Zhang, Yu Zhang, Yonghao Gai
DOI: 10.1016/j.matdes.2026.116319
Cited by: 1
References: 40

Abstract

• Engineered a novel Cu-TCPP MOF-based nanoparticle to induce ferroptosis. • Enhanced ferroptosis via synergistic ROS generation and GSH depletion-triggered lipid peroxidation. • Provides a promising strategy to boost ferroptosis therapy efficacy in vivo .

Fields of Study & Subjects

Ferroptosis and cancer prognosis Nanoplatforms for cancer theranostics Advanced Nanomaterials in Catalysis

Publication details

Journal / source
Materials & Design
Publisher
Elsevier BV
Volume
267
Pages
116319–116319
Publication date
1 June 2026
Language
EN