Assessment of Myocardial Stiffness in Healthy Adults by Magnetic Resonance Elastography: Effects of Slice Location and Demographic Factors

Meta-Radiology 2026 Open access

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Authors: Yong Cheng, Shutian An, Zhen Wang, Yewen Jiang, Z. M. Zheng, Zhanglei Li, Yi-Xiang Wang, Jun Chen, Yongqiang Yu, Ren Zhao, Xiaohu Li
DOI: 10.1016/j.metrad.2026.100220
Cited by: 1
References: 36

Abstract

To establish normal myocardial stiffness values in healthy adults using cardiac MR elastography (MRE) and assess the impact of slice location and demographic factors. 125 healthy volunteers underwent cardiac MRE using a 140-Hz vibration frequency, with data acquired during early systole (approximately 100 ms after the R-wave). Stiffness was measured in basal, mid, and apical short-axis views. Statistics included repeated-measures ANOVA (slice locations), t-tests (sex), Spearman correlation (age), and multivariable linear regression (controlling for age, sex, body mass index, and body surface area). Global myocardial stiffness was 8.1 ± 1.1 kPa. A significant apical-to-basal gradient existed (apex: 8.7 ± 1.1, mid: 8.3 ± 1.2, base: 7.4 ± 1.3 kPa; all P

Fields of Study & Subjects

Ultrasound Imaging and Elastography Cardiovascular Function and Risk Factors Cardiovascular Health and Disease Prevention

Publication details

Journal / source
Meta-Radiology
Publisher
Elsevier BV
Volume
4
Issue
2
Pages
100220–100220
Publication date
18 April 2026
Language
EN