Structural design and mechanical analysis of cerebral venous sinus thrombolytic stents

Materials Letters X 2026 Open access

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Authors: Xiaofeng Cao, Yu‐Chen Fan, Guanjun Chen, H Y Liu, Sijin Li, Miaowen Jiang, Min Li, Xunming Ji, Xiaofei Han, Yufeng Zheng
DOI: 10.1016/j.mlblux.2026.100272
Cited by: 0
References: 11

Abstract

Cerebral venous sinus thrombosis (CVST) poses treatment challenges due to fundamental anatomical differences between venous and arterial systems, for which conventional arterial thrombectomy devices are suboptimal. We present a manually adjustable braided NiTi stent retriever designed for CVST that enables real-time control of radial force and thrombus engagement. Finite element analysis demonstrated uniform stress distribution under tensile, compressive, and bending loads. Mechanical tests confirmed low radial force and high flexibility, while deployment in a human venous sinus model showed excellent conformability. This stent overcomes key limitations in venous thrombectomy, providing a promising foundation for CVST-specific devices.

Fields of Study & Subjects

Cerebral Venous Sinus Thrombosis Vascular Malformations Diagnosis and Treatment Thyroid and Parathyroid Surgery

Publication details

Journal / source
Materials Letters X
Publisher
Elsevier BV
Volume
27
Pages
100272–100272
Publication date
15 May 2026
Language
EN