Cohesin cofactor dosage sets the rate of loop extrusion, rendering genome folding tunable yet vulnerable to genetic disruption

Molecular Cell 2026 Open access

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Authors: Rini Shah, Maxime M. C. Tortora, Nessim Louafi, Hadi Rahmaninejad, Karissa Hansen, Erika C. Anderson, Kenya Bonitto, David Wen, Luca Giorgetti, Geoffrey Fudenberg, Elphège P. Nora
DOI: 10.1016/j.molcel.2026.03.037
Cited by: 4
References: 109

Fields of Study & Subjects

Genomics and Chromatin Dynamics Microtubule and mitosis dynamics DNA Repair Mechanisms

Publication details

Journal / source
Molecular Cell
Publisher
Elsevier BV
Volume
86
Issue
9
Pages
1635–1652.e8
Publication date
23 April 2026
Language
EN