Stepwise DNA-unwinding gates TnpB genome-editing activity

Molecular Cell 2026 Open access

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Authors: Zehan Zhou, Iren Saffarian-Deemyad, Honglue Shi, Trevor Weiss, Muhammad Moez ur-Rehman, Kamakshi Vohra, Petr Skopintsev, Peter H. Yoon, Marena I. Trinidad, Conner J. Langeberg, Maris Kamalu, Jasmine Amerasekera
+13 more Yuxing Zhou, Erin Doherty, Kevin D.P. Aris, Noor Al-Sayyad, Brittney W. Thornton, Rachel F. Weissman, Kevin M. Wasko, Isabel Esain-Garcia, Evan C. DeTurk, David F. Savage, Steven E. Jacobsen, Zev Bryant, Jennifer A. Doudna
DOI: 10.1016/j.molcel.2026.07.015
Cited by: 1
References: 71

Fields of Study & Subjects

CRISPR and Genetic Engineering Bacterial Genetics and Biotechnology RNA regulation and disease

Publication details

Journal / source
Molecular Cell
Publisher
Elsevier BV
Volume
86
Issue
16
Pages
3154–3166.e11
Publication date
1 August 2026
Language
EN