Design, synthesis, ADMET profiling, POM analysis and molecular dynamics studies of coumarin-DAPY derivatives as HIV-1 reverse transcriptase inhibitors

Mustapha Suleiman; Syazwani Itri Amran; Kumitaa Theva Das; Murugesan Sankaranarayanan; Taïbi Ben Hadda; Faisal A. Almalki; Daryn Benson; Joazaizulfazli Jamalis

doi:10.1016/j.molstruc.2026.145278

Design, synthesis, ADMET profiling, POM analysis and molecular dynamics studies of coumarin-DAPY derivatives as HIV-1 reverse transcriptase inhibitors

Journal of Molecular Structure 2026

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Authors: Mustapha Suleiman, Syazwani Itri Amran, Kumitaa Theva Das, Murugesan Sankaranarayanan, Taïbi Ben Hadda, Faisal A. Almalki, Daryn Benson, Joazaizulfazli Jamalis

DOI: 10.1016/j.molstruc.2026.145278

Cited by: 2

References: 45

Fields of Study & Subjects

HIV/AIDS drug development and treatment Synthesis and biological activity Computational Drug Discovery Methods

Publication details

Journal / source: Journal of Molecular Structure
Publisher: Elsevier BV
Volume: 1358
Pages: 145278–145278
Publication date: 10 January 2026
Language: EN

References 45