Membrane-camouflaged metal-phenolic nanomedicines for the treatment of ischemic stroke via relieving oxidative stress and neuroinflammation

Materials Today Bio 2026 Open access

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Authors: Bingyuan Liu, X P Chen, Luyun Tu, Lixin Yin, Hongxia Huang, Y Wu, Hui Cai, Yiliang Li, Sheng Hong
DOI: 10.1016/j.mtbio.2026.103392
Cited by: 1
References: 36

Abstract

, the nanomedicine can effectively scavenge reactive oxygen species, inhibit lipid peroxidation, and enhance cell survival. In murine middle cerebral artery occlusion models, M@EFE NPs could reduce infarct volume, attenuate neuronal apoptosis and neuroinflammation, and improve motor recovery and long-term survival. This study presents a promising combinatorial nanotherapeutic strategy for ischemic stroke, providing insights into biomimetic nanomedicine for treating cerebral IRI.

Fields of Study & Subjects

Neuroinflammation and Neurodegeneration Mechanisms Advanced Nanomaterials in Catalysis Hydrogen's biological and therapeutic effects

Publication details

Journal / source
Materials Today Bio
Publisher
Elsevier BV
Volume
39
Pages
103392–103392
Publication date
22 June 2026
Language
EN