Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus

New Biotechnology 2026 Open access

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Authors: Zeynep Efsun Duman‐Özdamar, Rudolf Marcel Veloo, Elena Tsepani, Mattijs K. Julsing, Vitor A.P. Martins dos Santos, Jeroen Hugenholtz, Maria Suarez-Diez
DOI: 10.1016/j.nbt.2026.01.017
Cited by: 2
References: 37

Abstract

and around 0.30 g lipids/g glycerol. In all, we established a cultivation strategy and strain that reached almost the theoretical maximum yield, and highest lipid content reported for a medium containing glycerol as a carbon source. These results strengthen the basis of using C. oleaginous as a platform for microbial oil production, thereby facilitating the development of processes substituting palm oil with a sustainable alternative.

Fields of Study & Subjects

Microbial Metabolic Engineering and Bioproduction Lipid metabolism and biosynthesis Enzyme Catalysis and Immobilization

Publication details

Journal / source
New Biotechnology
Publisher
Elsevier BV
Volume
93
Pages
1–8
Publication date
5 February 2026
Language
EN