Impact of middle meningeal artery embolization timing on chronic subdural hematoma resolution and functional outcomes

Journal of Neuroradiology 2026 Open access

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Authors: Bluyé DeMessie, Muhammed Amir Essibayi, Hamza Adel Salim, Alireza Karandish, Nathan Farkas, Deepak Khatri, Neil Haranhalli, Amanda Baker, Richard L. Zampolin, Allan L. Brook, Seon-Kyu Lee, Nimer Adeeb
+75 more James T. Grist, Fulvio Zaccagna, Yan-Lin Li, Davide Simonato, Diego Alejandro Ortega, Nicole Mariantonia Cancelliere, Jose Danilo Diestro, Dhairya A. Lakhani, Joseph A. Carnevale, Craig Schreiber, Atakan Orscelik, Zachary Abecassis, Spencer Raub, Georgios S. Sioutas, Giancarlo Salsano, Svetlana Kvint, Andrew Falzon, Vance Cantrell, Brian Holliday, Jefferson O. Abaricia, Pedram Daniel Maleknia, Leonardo Cruz‐Criollo, Samantha J. Schimmel, Basel Musmar, Matthew David Alexander, Jorge Rios Zermeno, Koul Prateeka, Ahmed Aljuboori, Dominik F. Vollherbst, Domagoj Gajski, Jared Cooper, Rahim Abo Kasem, Sami Al Kasab, Alejandro M. Spiotta, Fawaz Al-Mufti, Vladimir Kalousek, Markus Alfred Möhlenbruch, Luca Scarcia, Clemens Maria Schirmer, Thien Huynh, Rabih G. Tawk, Fabio Settecase, Stavropoula Tjoumakaris, Pascal M. Jabbour, Kunal V. Vakharia, Mario Zanaty, Santiago Ortega‐Gutierrez, Jesse George Atherton Jones, Marco Colasurdo, Hussein H. Nasser, Sri Hari Sundararajan, Pascal J. Mosimann, Erez Nossek, Eytan Raz, Lucio Castellan, Bruno Del Sette, Caterina Michelozzi, Davide Saraceno, Pietro Panni, Visish Srinivasan, Jan-Karl Burkhardt, Gaultier Marnat, Pietro Mario Santini, Michael R. Levitt, Giuseppe Lanzino, Waleed Brinjikji, Jared Knopman, Tareq Kass‐Hout, Julian Spears, Thomas R. Marotta, Max Wintermark, Vitor Mendes Pereira, Maurizio Fuschi, Adam A. Dmytriw, David Altschul
DOI: 10.1016/j.neurad.2026.101584
Cited by: 1
References: 24

Abstract

BACKGROUND AND PURPOSE: Chronic subdural hematoma (cSDH) affects approximately 20 per 100,000 individuals annually, with surgical recurrence rates of 10-20%. Middle meningeal artery embolization (MMAE) has emerged as a promising minimally invasive treatment, but the optimal timing remains unclear. We evaluated the association between MMAE timing and radiological and functional outcomes in cSDH. METHODS: We conducted a retrospective multicenter international cohort study across 33 centres, including patients who underwent MMAE for cSDH between January 2018 and December 2024. Patients were stratified by timing from diagnosis: Q1 (≤1 day), Q2 (2 days), Q3 (3-6 days), and Q4 (>6 days). The primary composite endpoint required radiological success (hematoma thickness

Fields of Study & Subjects

Neurosurgical Procedures and Complications Traumatic Brain Injury and Neurovascular Disturbances Cerebral Venous Sinus Thrombosis

Publication details

Journal / source
Journal of Neuroradiology
Publisher
Elsevier BV
Volume
53
Issue
5
Pages
101584–101584
Publication date
10 July 2026
Language
EN