More than microglial depletion: PLX5622 activates the hepatic constitutive androstane receptor to alter anesthesia and addiction

Neuron 2026

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Authors: Kelei Cao, Cheng Wang, Liyao Qiu, Zexi Wang, Y Zhao, Y. Yuan, Weiying Wu, Jing Xue, Linghui Zeng, Zhi-Ying Wu, Huan Ma, Tingjun Hou

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David A. Hume, Cunqi Ye, Shumin Duan, Zhihua Gao

DOI: 10.1016/j.neuron.2025.12.044

Cited by: 6

References: 78

Fields of Study & Subjects

Neuroinflammation and Neurodegeneration Mechanisms Pain Mechanisms and Treatments Neuropeptides and Animal Physiology

References 78