First-in-human pharmacological characterization of the novel NMDA receptor antagonist GM-1020: a single ascending dose study in healthy participants

Neuroscience Applied 2026 Open access

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Authors: S. Makai-Bölöni, G. Marek, D. Umbricht, C. Ed, J. Winters, D. Dvorak, S. Raynes, Z. Hughes, E. Austin, A. Klein, W. Leong, F. Krol

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M. Otto, L. Borghans, A. Kruegel, J. Sporn, G. Jacobs

DOI: 10.1016/j.nsa.2025.106150

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Fields of Study & Subjects

Neuroscience and Neuropharmacology Research Pharmacological Receptor Mechanisms and Effects Nicotinic Acetylcholine Receptors Study