Assessment of spatial memory and cognitive flexibility in diabetes type 2 in middle-aged Sprague-Dawley rats of both sexes

Neuroscience Applied 2026 Open access

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Authors: K. Jezdić, J. Ivanović, V. Todorović, A. Santrač, M. Savić M, J. Aranđelović
DOI: 10.1016/j.nsa.2025.106262
Cited by: 0

Abstract

Metabolic changes caused by obesity and the development of diabetes type 2 (T2D) can lead to cognitive impairment. Indeed, it occurred to be a common complication of T2D. Thus, problems with spatial memory are one of the first symptoms of memory loss in patients with T2D. In addition, T2D is associated with changes in the hippocampus and prefrontal cortex, which may also underlie executive function impairment. ...

Fields of Study & Subjects

Memory and Neural Mechanisms Neurological Disease Mechanisms and Treatments Dementia and Cognitive Impairment Research

Publication details

Journal / source
Neuroscience Applied
Volume
5
Pages
106262–106262
Publication date
1 January 2026
Language
EN