Enhancing protein expression in humans through codon optimization with transformer and contrastive learning

Molecular Therapy — Nucleic Acids 2026 Open access

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Authors: Juseong Kim, Jeongmu Kim, Jae‐Wook Lee, Qian Qi, Caroline Danehy, Ho Young Kang, Yong Cheng, Giltae Song

DOI: 10.1016/j.omtn.2026.102991

Cited by: 1

References: 60

Abstract

experiments, enhance protein expression through optimized codon usage and improved mRNA stability.

Machine Learning in Bioinformatics Gene expression and cancer classification RNA and protein synthesis mechanisms

References 60