Virus-based IFNγ gene delivery and photodynamic therapy cooperate to remodel the tumor microenvironment and suppress breast cancer

Molecular Therapy Oncology 2026 Open access

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Authors: Ksenija Korotkaja, Zhanna Rudevica, Darija Lapina, Dace Skrastina, Juris Jansons, Olga Nilova, Karīna Spunde, Anna Zajakina
DOI: 10.1016/j.omton.2025.201124
Cited by: 0
References: 82

Abstract

macrophages, MDSCs), creating a more immunostimulatory tumor microenvironment. This research contributes to our understanding of the synergistic potential between SFV/IFNγ therapy and PDT in breast cancer treatment.

Fields of Study & Subjects

Immune cells in cancer Photodynamic Therapy Research Studies Nanoplatforms for cancer theranostics

Publication details

Journal / source
Molecular Therapy Oncology
Volume
34
Issue
1
Pages
201124–201124
Publication date
3 January 2026
Language
EN