Improved oncolytic and immunostimulatory activity of the spontaneous jin-3 reovirus mutant in preclinical bladder cancer models

Molecular Therapy Oncology 2026 Open access

Read full text
Authors: Arjanneke F. van de Merbel, Maaike H. van der Mark, Lobke C.M. Hensen, Diana J.M. van den Wollenberg, Rob C. Hoeben, Willemijn C.G. Zonneveld, Rob C.M. Pelger, Maxime T. M. Kummeling, Geertje van der Horst, Gabri van der Pluijm
DOI: 10.1016/j.omton.2026.201128
Cited by: 1
References: 94

Abstract

reoviruses elicit robust immunostimulatory responses, highlighting their potential as candidate agents for clinical translation in UCB.

Fields of Study & Subjects

Virus-based gene therapy research Viral gastroenteritis research and epidemiology Cancer Research and Treatments

Publication details

Journal / source
Molecular Therapy Oncology
Publisher
Elsevier BV
Volume
34
Issue
1
Pages
201128–201128
Publication date
14 January 2026
Language
EN