Retrieval-augmented reasoning reshapes collective reliability in text-based radiology question answering

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Authors: Mina Farajiamiri, Jeta Sopa, Saba Afza, Lisa C. Adams, Felix Barajas Ordonez, Tri-Thien Nguyen, Mahshad Lotfinia, Sebastian Wind, Keno Bressem, Sven Nebelung, Daniel Truhn, Soroosh Tayebi Arasteh
Cited by: 1
References: 42

Abstract

Retrieval-augmented reasoning pipelines are increasingly used to structure how large language models (LLMs) incorporate external evidence in clinical question answering, but their reliability under model variability remains unclear. We evaluated 34 LLMs on 169 expert-curated, text-only, multiple-choice radiology questions, comparing zero-shot inference with a fixed shared-evidence condition in which all models received identical structured evidence reports before answer selection. Primary endpoints were inter-model decision dispersion and panel-based robustness of correctness. Shared evidence reduced decision dispersion (median entropy 0.48→0.13; p = 5.6 × 10 −9 ) and increased robustness of correctness (mean 0.74→0.81; p = 5.6 × 10 −9 ). Majority consensus increased, and consensus strength remained strongly correlated with robustness. However, high agreement did not guarantee correctness, and rare high-consensus failures persisted. These findings show that shared evidence can improve reproducibility under model variability, but accuracy and agreement alone are insufficient to characterize reliability.

Fields of Study & Subjects

Artificial Intelligence in Healthcare and Education Topic Modeling Radiology practices and education

Publication details

Journal / source
Patterns
Publisher
Elsevier BV
Volume
7
Issue
10
Pages
101639–101639
Publication date
1 August 2026
Language
EN