The “good” future is a mirage? – hyperdiploidy in childhood acute lymphoblastic leukemia

Pediatric Hematology Oncology Journal 2026 Open access

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Authors: Vijayshree Muthukumar, Indhumathi Nagarathinam, Kavitha Ganesan, Ramya Uppuluri, Revathi Raj
DOI: 10.1016/j.phoj.2026.100805
Cited by: 1
References: 5

Abstract

• Review of cytogenetics in hyper diploid ALL of cytogenetics on Day 28 is feasible and can be implemented in all centres with cytogenetics data. • Duplicated hyper haploids chromosome 1q duplication, chromosome 6q deletion, isochromosome 17q, isochromosome 7q, and TP53 mutation may be associated with non-classical hyperdiploidy. • There is no added cost of this test for risk stratification which adds to the economic burden in resource-limited settings but a simple review of the cytogenetics data.

Fields of Study & Subjects

Acute Lymphoblastic Leukemia research Chronic Myeloid Leukemia Treatments Acute Myeloid Leukemia Research

Publication details

Journal / source
Pediatric Hematology Oncology Journal
Publisher
Elsevier BV
Volume
11
Issue
1
Pages
100805–100805
Publication date
16 February 2026
Language
EN