Integrated network pharmacology and UHPLC–Q–TOF LC–MS/MS phytochemical profiling demonstrate tilianin-mediated restoration of PDE10A/cAMP/PKA/CREB signaling in an MK-801-induced schizophrenia-like model

Phytomedicine 2026

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Authors: Ye Eun Cho, Hyeon-Bae Park, Ramachandran Chelliah, So-Yeon Kim, So-Young Cho, Su Jung Lee, Ye-Won Lee, Seon-Woo Lee, Na-Hyun Lee, Xiang-Qian Liu, Seung Hwan Son, Sanghyun Lee
+4 more Jong Hoon Ryu, Deog Hwan Oh, Ho Jung Bae, Se Jin Park
DOI: 10.1016/j.phymed.2026.158394
Cited by: 1
References: 81

Fields of Study & Subjects

Phosphodiesterase function and regulation Neurotransmitter Receptor Influence on Behavior Protein Kinase Regulation and GTPase Signaling

Publication details

Journal / source
Phytomedicine
Publisher
Elsevier BV
Volume
158
Pages
158394–158394
Publication date
6 June 2026
Language
EN