Development of monoclonal antibodies for GoAstV-2 VP27 protein and precise mapping of linear antigenic epitopes
Abstract
was the minimal epitope recognized by mAb 11-39B. Homology and structural analyses demonstrated that the epitope was situated on the surface of the VP27 protein and exhibited high conservation among GoAstV-2 strains but exhibited significant differences in the GoAstV-1 serotype. Our study contributes to a better understanding of the GoAstV-2 VP27 antigenic region and provides a basis for establishing epitope-based GoAstV-2 diagnostic methods and vaccine development.
Fields of Study & Subjects
Viral gastroenteritis research and epidemiology
Virus-based gene therapy research
Celiac Disease Research and Management
Publication details
- Journal / source
- Poultry Science
- Publisher
- Elsevier BV
- Volume
- 105
- Issue
- 4
- Pages
- 106535–106535
- Publication date
- 28 January 2026
- Language
- EN