Structural and regulatory principles underlying apicomplexan conoid function

Trends in Parasitology 2026 Open access

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Authors: Albert Tell i Puig, Dominique Soldati‐Favre
DOI: 10.1016/j.pt.2026.01.002
Cited by: 0
References: 8

Abstract

Zeng et al. and Qian et al. reveal in their cryogenic electron microscopy (cryo-EM) studies how apicomplexan parasites extensively remodel tubulin to construct the conoid, a specialized invasion organelle. Distinct microtubule assemblies integrate mechanical support, force generation, and secretion control, providing a structural framework that underpins parasite motility and host cell entry.

Fields of Study & Subjects

Toxoplasma gondii Research Studies Microtubule and mitosis dynamics Advanced Electron Microscopy Techniques and Applications

Publication details

Journal / source
Trends in Parasitology
Volume
42
Issue
3
Pages
153–155
Publication date
6 February 2026
Language
EN